1. Billy Loomis and Stu Macher
Billy Loomis and Stu Macher are the first killers in the Scream franchise, responsible for the original Woodsboro murders. They targeted Sidney Prescott, Casey Becker, and others in a staged killing spree to frame Sidney's father. Forbes notes that Billy is revealed as Sidney's half-brother, motivated by parental betrayal. Stu is killed by Sidney in the final confrontation, while Billy is shot and later reanimated in the finale.
Their killing order began with Casey Becker, followed by Principal Himbry, and culminated in the attempted murder of Sidney and her mother. Billy used a Ghostface costume and phone calls to manipulate victims. Their plan collapsed when Sidney turned the tables, leading to Stu's death and Billy's final defeat.
2. Mickey Altieri
Background and Motive
Mickey Altieri is the second major killer in the Scream order, appearing in Scream 2. He is a film-obsessed student who idolizes horror movie killers and seeks infamy through a new wave of murders. Wikipedia states that Mickey killed multiple students at Windsor College, including Randy Meeks, in a bid to become the ultimate copycat.
Killing Sequence and Outcome
Mickey's killing sequence began with the murder of a student during a campus party, escalating to the death of Randy Meeks. He was ultimately shot by Sidney and then killed by Gale Weathers. His motive was to prove that anyone could become a killer and to gain notoriety in the media.
3. Debbie Loomis
Role in the Franchise
Debbie Loomis, Billy's mother, is the third killer in the Scream order, revealed in Scream 3. She orchestrated the original Woodsboro murders to avenge Billy's death and to punish Sidney. SEC filings related to entertainment companies show how franchise rights can shift, but Debbie's motive remained personal revenge.
Final Confrontation
Debbie's killing spree targeted Sidney and those close to her, including the attempt to kill Sidney's friend. She was ultimately killed by Sidney in the climax of Scream 3. Her death marked the end of the original Ghostface copycat storyline and set the stage for future killers.